When and How to Take the Beta hCG Test | Low hCG Levels, IVF & Sonography Explained

The journey toward motherhood often begins with a small but powerful hormone — human chorionic gonadotropin (hCG). This hormone is one of the first indicators of pregnancy and plays a crucial role in supporting it during its earliest days.

Understanding when to take the Beta hCG test, what the values mean, and how to interpret low levels is essential for women trying to conceive — whether naturally or through fertility treatments like IVF. This guide breaks down everything you need to know about the Beta hCG test, its significance, and what comes next in early pregnancy monitoring.


What Is the Beta hCG Test?

The Beta hCG test (Beta Human Chorionic Gonadotropin) is a blood test used to detect and measure the exact amount of hCG in a woman’s bloodstream.

After fertilization, the embryo implants in the uterine lining, and the placenta begins to produce hCG. The hormone helps maintain the corpus luteum, which secretes progesterone to support the early stages of pregnancy until the placenta fully develops.

A Beta hCG test is more accurate and sensitive than a urine pregnancy test. While home tests detect only the presence of hCG, the Beta hCG blood test measures the exact level, providing valuable insights into the progress and health of the pregnancy.


When Should You Take the Beta hCG Test?

Timing is key for an accurate hCG result.

  • After Natural Conception:
    The test can be taken about 10–12 days after ovulation or embryo implantation, typically around the time of a missed period. Testing too early can lead to false negatives because hCG levels may not have risen enough yet.

  • After IVF or IUI:
    In fertility treatments like IVF (In Vitro Fertilization) or IUI (Intrauterine Insemination), the Beta hCG test is usually done 12–14 days after the embryo transfer or insemination.

  • Repeat Testing:
    Doctors often recommend repeating the test after 48–72 hours to check if hCG levels are rising appropriately. A healthy pregnancy typically shows a doubling of hCG levels every two to three days in early weeks.


What Value Confirms Pregnancy?

The presence of hCG in the blood confirms pregnancy, but quantitative values help determine how far along it may be and whether it’s progressing normally.

Here’s a general reference guide for Beta hCG levels in early pregnancy:

Days After OvulationExpected hCG Level (mIU/ml)
10 days10–25
14 days (around missed period)50–300
4 weeks gestation100–1,000
5 weeks1,000–10,000
6 weeks10,000–100,000

A value above 25 mIU/ml is generally considered positive for pregnancy. However, a single value cannot determine viability — what’s most important is how the number changes over time.


What If hCG Levels Are Low?

Low or slowly rising hCG levels can be a sign that the pregnancy is not progressing normally. However, they must always be interpreted with caution and in context.

1. Weak or Non-viable Embryo

In some cases, low hCG levels indicate that the embryo has stopped developing or that implantation was weak. This may result in an early miscarriage, often before a pregnancy becomes visible on ultrasound.

2. IVF or Assisted Conception Cases

In IVF cycles, hCG levels can vary widely depending on the number of embryos transferred, the timing of implantation, and the individual hormonal response. Even if the initial value is low, the trend (rising pattern) is what truly matters.
A slow but steady increase may still lead to a healthy pregnancy, while a sharp drop often signals an early loss.

3. Ectopic Pregnancy

An ectopic pregnancy occurs when the embryo implants outside the uterus, most commonly in the fallopian tube.
Here, hCG levels typically rise more slowly than expected and do not double every 48–72 hours.
Symptoms such as abdominal pain, spotting, or dizziness require immediate medical attention. Early diagnosis through Beta hCG tracking and ultrasound is essential to prevent complications.


How Long Should Medicines Be Continued?

After a positive Beta hCG test, fertility specialists often prescribe hormonal support medications, especially in IVF or high-risk pregnancies.

These medicines help maintain the uterine lining and support early embryo growth until the placenta takes over hormone production — typically around 10–12 weeks of pregnancy.

  • In natural conception, hormonal support may not be necessary unless progesterone deficiency is detected.

  • In IVF or IUI, medication continuation depends on your doctor’s advice, hCG trends, and early ultrasound findings.

Never discontinue prescribed medications on your own, even if hCG levels are rising well. Sudden withdrawal of progesterone can cause complications or pregnancy loss.


When Does Pregnancy Become Visible in Sonography?

While Beta hCG confirms pregnancy biochemically, ultrasound confirms it visually.
The timing of visibility depends on hCG levels and gestational age.

  • Gestational sac: Visible on transvaginal ultrasound when hCG reaches around 1,500–2,000 mIU/ml (approximately 5 weeks).

  • Yolk sac: Usually seen by 5.5 weeks.

  • Fetal pole with heartbeat: Typically visible around 6–6.5 weeks when hCG is about 10,000 mIU/ml or higher.

If the pregnancy is not visible even after the hCG level crosses 2,000 mIU/ml, your doctor may suspect an ectopic pregnancy or delayed implantation and will monitor you closely.


Key Takeaways

  • The Beta hCG test is a vital tool for confirming and monitoring early pregnancy.

  • Testing too early can lead to confusion — timing and follow-up are essential.

  • A doubling hCG pattern every 48–72 hours indicates a healthy pregnancy.

  • Low or abnormal hCG trends may suggest an ectopic or non-viable pregnancy, requiring careful medical evaluation.

  • Medications should be continued as advised until the pregnancy is stable and visible on ultrasound.

  • Early ultrasound confirmation is usually possible once hCG levels exceed 1,500–2,000 mIU/ml.


Final Thoughts

Pregnancy is a delicate process where every number and milestone matters — especially in the first few weeks. Understanding Beta hCG levels helps couples navigate the uncertainty of early pregnancy with greater confidence and awareness.

Whether you have conceived naturally or through fertility treatments, regular monitoring, timely follow-up, and professional guidance are key to ensuring a healthy outcome.

At Patki Hospital, Kolhapur, we specialize in fertility care, pregnancy monitoring, and reproductive health — offering accurate Beta hCG testing, personalized treatment plans, and compassionate support every step of the way.